Ketamine for Depression Care.

An established treatment approach focused on lasting change, not just symptom relief.

A different way forward.

Living with depression can feel overwhelming, especially when standard treatments haven’t led to the change you hoped for.

Ketamine therapy has been studied in clinical settings as an alternative approach that may help people move beyond symptom management by addressing deeper patterns related to mood, trauma, and emotional regulation. When delivered with proper preparation and therapeutic support, it may offer a different path forward.

Exploring Ketamine for Depression.

Depression can be complex, and its underlying causes are not always fully understood. Ketamine has been studied in clinical settings as an alternative approach, particularly for individuals who have not experienced sufficient improvement with standard treatments.

At EntheoMed, ketamine therapy is offered through the Odyssey Method, a structured, medically supervised approach that integrates assessment, therapy, and ongoing guidance to support sustainable change before and after treatment.

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Ketamine Therapy for Depression, Delivered With Medical Care

Clinically Proven

Ketamine has been studied in clinical settings for its role in treating depression, particularly for individuals who have not found adequate support from standard treatments alone.

Multi-Session Care

Ketamine therapy is typically offered as part of a structured, multi-session approach, with preparation and integration support designed to help people make use of the therapeutic window following treatment and sustain meaningful change over time.

Medically Supervised

All ketamine for depression treatments at EntheoMed are delivered under medical supervision, with thorough screening and ongoing oversight to prioritize safety, screening, and appropriateness of care.

Odyssey session entheomed

How does ketamine work for depression?

  • Ketamine works differently than traditional antidepressants by acting on the brain’s glutamate system, which plays a role in learning, memory, emotional regulation, and how the brain adapts to new experiences.
  • In clinical studies, ketamine has been shown to temporarily increase neuroplasticity, helping the brain form new connections. This time-limited window may support shifts in mood and perspective when paired with therapeutic support.

Your Odyssey Method Experience.

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Discovery

The Odyssey Care Team gets to know you and ensures you’re a fit for ketamine therapy. Receive your ketamine consultation with both a mental health and physical review.

– Where and how do you feel stuck?

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Orientation

Set your intention and have a preparation counselling session to get ready mentally and emotionally for your treatment. Proper preparation helps support a safe and meaningful experience.

– What do you really want?

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Experience

Therapeutic ketamine experience with medical support and care in a safe, calming environment.

A physician and nurse will be with you every step of the way.

– What have you been resisting?

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Integration

Deepen your understanding and integrate insights from your ketamine experience with tailored support from our team.

– What changes do you want to make?

Why Choose the Odyssey Method?

Odyssey is our personalized, science-informed, medically directed approach to ketamine-assisted therapy, designed to support people navigating depression and other mental health challenges through structured care before and after treatment.

  • Intramuscular ketamine treatment delivered under medical supervision

  • Sessions held in a calm, private environment designed to support safety, comfort, and nervous system regulation

  • Online preparation and integration support with trained counsellors to help translate insights into lasting change

  • Ongoing access to Odyssey Online, including educational and mind-body resources to support ongoing regulation and integration

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Frequently Asked Questions

Ketamine works differently than many traditional antidepressants. Rather than primarily targeting serotonin, it acts on the brain’s glutamate system, which plays a role in mood, learning, and emotional flexibility.

In supervised clinical settings, ketamine may help create a temporary window of increased neuroplasticity. This window can support therapeutic work when combined with counselling, preparation, and integration support.

The effects of ketamine for depression can vary from person to person. In clinical settings, many individuals experience a therapeutic window that may last from several days to a few weeks following a session.

Because this window is temporary, ketamine therapy is typically offered as part of a structured, multi-session approach that includes preparation and integration support. Some people may benefit from periodic maintenance sessions over time, while others space treatments further apart as they build supportive habits and coping strategies.

When used in a medical setting, ketamine therapy is very different from recreational use. At EntheoMed, ketamine is administered at controlled doses under medical supervision, with thorough screening and no take-home medication.

Current clinical research suggests that the risk of addiction is low when ketamine is used appropriately within a structured, supervised care model that includes preparation and integration.